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Mouse Anti-TCEAL1 Recombinant Antibody (CBYJT-2230) (CBMAB-T1338-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TCEAL1 (Transcription Elongation Factor A Like 1). The antibody can be used for immunoassay techniques, such as WB, IHC.
See all TCEAL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2230
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
Full length human recombinant protein of human TCEAL1 (NP_004771) produced in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
transcription elongation factor A (SII)-like 1
Introduction
TCEAL1 is a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may play a role as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. TCEAL1 may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome.
Entrez Gene ID
9338
UniProt ID
Q15170
Alternative Names
Transcription Elongation Factor A Like 1; Transcription Elongation Factor S-II Protein-Like 1; Transcription Elongation Factor A (SII)-Like 1; Nuclear Phosphoprotein P21/SIIR; TCEA-Like Protein 1; SIIR
Function
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
Cellular Location
Nucleus
PTM
Phosphorylation of Ser-38 and Ser-39 is critical for transcriptional repression.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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