TEX11

Tex11 is a regulator of crossing-over during meiosis. It is Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.

Full Name

Testis Expressed gene 11

Function

Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.

Biological Process

Biological Process apoptotic processSource:Ensembl
Biological Process chiasma assemblySource:Ensembl
Biological Process ectopic germ cell programmed cell deathSource:Ensembl
Biological Process fertilizationSource:Ensembl
Biological Process male gonad developmentSource:Ensembl
Biological Process male meiosis chromosome segregationSource:GO_Central1 Publication
Biological Process meiotic gene conversionSource:UniProtKB
Biological Process negative regulation of apoptotic processSource:Ensembl
Biological Process negative regulation of developmental processSource:Ensembl
Biological Process negative regulation of reproductive processSource:Ensembl
Biological Process reciprocal meiotic recombinationSource:UniProtKB
Biological Process resolution of meiotic recombination intermediatesSource:Ensembl
Biological Process synaptonemal complex assemblySource:GO_Central1 Publication

Involvement in disease

Spermatogenic failure, X-linked, 2 (SPGFX2):
An infertility disorder caused by spermatogenesis defects. It is characterized by mixed testicular atrophy and azoospermia with meiotic arrest.