THSD1

Thsd1 has a broad expression in lung adult (RPKM 7.1), bladder adult (RPKM 3.0) and 25 other tissues.
Full Name
Thrombospondin, Type I, Domain 1
Function
Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
Biological Process
Focal adhesion assembly
Cellular Location
Isoform 1
Endosome membrane
Cell junction, focal adhesion
Localizes to nascent focal adhesions.
Isoform 2
Membrane
Isoform 3
Secreted
Involvement in disease
Aneurysm, intracranial berry, 12 (ANIB12):
A form of cerebral aneurysm, a focal abnormal dilatation of a blood vessel in the brain. Berry intracranial aneurysms, also known as saccular aneurysms, have a characteristic rounded shape and account for the vast majority of intracranial aneurysms. They are the most common cause of non-traumatic subarachnoid hemorrhage, a sudden-onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension, and excessive alcohol intake are associated with subarachnoid hemorrhage.
Topology
Extracellular: 25-413
Helical: 414-434
Cytoplasmic: 435-852
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Anti-THSD1 antibodies

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Target: Thsd1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: TX17.10
Application*: F, IP, WB, IC
Target: Thsd1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYJT-3049
Application*: WB, IP, IC, F
Target: Thsd1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-3048
Application*: E, WB
Target: Thsd1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYJT-3047
Application*: F, IC, IP, WB
Target: THSD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3045
Application*: F
Target: THSD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3044
Application*: F
Target: THSD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3043
Application*: F, MC
Target: THSD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3042
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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