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Mouse Anti-THSD1 Recombinant Antibody (CBYJT-3042) (CBMAB-T2299-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to THSD1 (Thrombospondin Type 1 Domain Containing 1). The antibody can be used for immunoassay techniques, such as FC.
See all THSD1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3042
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
NS0-derived, recombinant human THSD1 (rhTHSD1; aa25-361; Accession # Q9JM61)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
NaCl, 0.5% BSA
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 25-361

Target

Full Name
Thrombospondin, Type I, Domain 1
Introduction
THSD1 contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins.
Entrez Gene ID
55901
UniProt ID
Q9NS62
Alternative Names
Thrombospondin Type 1 Domain Containing 1; Transmembrane Molecule With Thrombospondin Module; TMTSP; Thrombospondin Type-1 Domain-Containing Protein 1; Thrombospondin, Type I, Domain Containing 1; Thrombospondin, Type I, Domain 1; 4833423O18Rik; UNQ3010
Function
Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
Biological Process
Focal adhesion assembly
Cellular Location
Isoform 1
Endosome membrane
Cell junction, focal adhesion
Localizes to nascent focal adhesions.
Isoform 2
Membrane
Isoform 3
Secreted
Involvement in disease
Aneurysm, intracranial berry, 12 (ANIB12):
A form of cerebral aneurysm, a focal abnormal dilatation of a blood vessel in the brain. Berry intracranial aneurysms, also known as saccular aneurysms, have a characteristic rounded shape and account for the vast majority of intracranial aneurysms. They are the most common cause of non-traumatic subarachnoid hemorrhage, a sudden-onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension, and excessive alcohol intake are associated with subarachnoid hemorrhage.
Topology
Extracellular: 25-413
Helical: 414-434
Cytoplasmic: 435-852
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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