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Rabbit Anti-Thsd1 Recombinant Antibody (CBYJT-3048) (CBMAB-T2305-YJ)

Provided herein is a Rabbit monoclonal antibody, which binds to Thsd1 (Thrombospondin, Type I, Domain 1). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all Thsd1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse
Clone
CBYJT-3048
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
Recombinant Mouse THSD1 protein. This antibody was obtained from a rabbit immunized with purified, recombinant Mouse THSD1
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Thrombospondin, Type I, Domain 1
Introduction
Thsd1 has a broad expression in lung adult (RPKM 7.1), bladder adult (RPKM 3.0) and 25 other tissues.
Entrez Gene ID
56229
UniProt ID
G3XA27
Alternative Names
Tmtsp; 4833423O18Rik
Function
Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix.
Biological Process
Focal adhesion assembly
Cellular Location
Isoform 1
Endosome membrane
Cell junction, focal adhesion
Localizes to nascent focal adhesions.
Isoform 2
Membrane
Isoform 3
Secreted
Involvement in disease
Aneurysm, intracranial berry, 12 (ANIB12):
A form of cerebral aneurysm, a focal abnormal dilatation of a blood vessel in the brain. Berry intracranial aneurysms, also known as saccular aneurysms, have a characteristic rounded shape and account for the vast majority of intracranial aneurysms. They are the most common cause of non-traumatic subarachnoid hemorrhage, a sudden-onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension, and excessive alcohol intake are associated with subarachnoid hemorrhage.
Topology
Extracellular: 25-413
Helical: 414-434
Cytoplasmic: 435-852
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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