TM4SF1
TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in different carcinomas.
Full Name
Transmembrane 4 L Six Family Member 1
Biological Process
Blastocyst formation
Cellular Location
Membrane
Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).
Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).
Topology
Cytoplasmic: 1-9
Helical: 10-30
Extracellular: 31-49
Helical: 50-70
Cytoplasmic: 71-93
Helical: 94-114
Extracellular: 115-161
Helical: 162-182
Cytoplasmic: 183-202
Helical: 10-30
Extracellular: 31-49
Helical: 50-70
Cytoplasmic: 71-93
Helical: 94-114
Extracellular: 115-161
Helical: 162-182
Cytoplasmic: 183-202
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Anti-TM4SF1 antibodies
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Target: TM4SF1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3446
Application*: F, IH, IC, MC
Target: TM4SF1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-202
Tag: Flag Tag
Target: TM4SF1
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B3
Application*: E, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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