TRIM54
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Full Name
tripartite motif-containing 54
Function
May bind and stabilize microtubules during myotubes formation.
Biological Process
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process microtubule-based process Source:UniProtKB1 Publication
Biological Process negative regulation of microtubule depolymerization Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication
Biological Process microtubule-based process Source:UniProtKB1 Publication
Biological Process negative regulation of microtubule depolymerization Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication
Cellular Location
Cytoplasm, cytoskeleton
Cytoplasm, myofibril, sarcomere, Z line
Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity).
Cytoplasm, myofibril, sarcomere, Z line
Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity).
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Anti-TRIM54 antibodies
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CompareTarget: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4817
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4816
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4815
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4814
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4813
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4812
Application*: WB, IH
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4811
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4810
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-4809
Application*: WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-3167
Application*: E, WB
Target: TRIM54
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-3166
Application*: WB, IH
Target: TRIM54
Sensitivity: 0.0053 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Trim54
Sensitivity: 0.0046 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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