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Mouse Anti-TRIM54 (AA 166-400) Recombinant Antibody (CBFYM-3166) (CBMAB-M3363-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-3166
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
Recombinant protein fragment corresponding to amino acids 166-400 of human TRIM54 (NP_115935) produced in E.coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 166-400

Target

Full Name
tripartite motif-containing 54
Introduction
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Entrez Gene ID
57159
UniProt ID
Q9BYV2
Alternative Names
Tripartite Motif Containing 54; Muscle-Specific RING Finger Protein 3; Ring Finger Protein 30; MURF-3; MuRF3; RNF30
Function
May bind and stabilize microtubules during myotubes formation.
Biological Process
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process microtubule-based process Source:UniProtKB1 Publication
Biological Process negative regulation of microtubule depolymerization Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication
Cellular Location
Cytoplasm, cytoskeleton
Cytoplasm, myofibril, sarcomere, Z line
Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity).
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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