Mouse Anti-TRIM54 (AA 166-400) Recombinant Antibody (CBFYM-3166) (CBMAB-M3363-FY)

Name: Mouse Anti-TRIM54 (AA 166-400) Recombinant Antibody (CBFYM-3166)
SKU: CBMAB-M3363-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYM-3166

Application

WB, IHC

Immunogen

Recombinant protein fragment corresponding to amino acids 166-400 of human TRIM54 (NP_115935) produced in E.coli

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 166-400

More Infomation

Target

Full Name

tripartite motif-containing 54

Introduction

The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Entrez Gene ID

57159

UniProt ID

Q9BYV2

Alternative Names

Tripartite Motif Containing 54; Muscle-Specific RING Finger Protein 3; Ring Finger Protein 30; MURF-3; MuRF3; RNF30

Function

May bind and stabilize microtubules during myotubes formation.

Biological Process

Biological Process cell differentiation Source:UniProtKB-KW
Biological Process microtubule-based process Source:UniProtKB1 Publication
Biological Process negative regulation of microtubule depolymerization Source:UniProtKB1 Publication
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication

Cellular Location

Cytoplasm, cytoskeleton
Cytoplasm, myofibril, sarcomere, Z line
Associates with microtubules. Localizes to the Z-lines in skeletal muscles (By similarity).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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