TSPAN8
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
Tetraspanin 8
Biological Process
Biological Process negative regulation of blood coagulation Source:Ensembl
Biological Process regulation of gene expression Source:Ensembl
Biological Process spermatogenesis Source:Ensembl
Biological Process regulation of gene expression Source:Ensembl
Biological Process spermatogenesis Source:Ensembl
Cellular Location
Membrane
Topology
Cytoplasmic: 1-9
Helical: 10-33
Extracellular: 34-57
Helical: 58-72
Cytoplasmic: 73-83
Helical: 84-109
Extracellular: 110-205
Helical: 206-230
Cytoplasmic: 231-237
Helical: 10-33
Extracellular: 34-57
Helical: 58-72
Cytoplasmic: 73-83
Helical: 84-109
Extracellular: 110-205
Helical: 206-230
Cytoplasmic: 231-237
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Anti-TSPAN8 antibodies
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CompareTarget: TSPAN8
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBYJT-5085
Application*: WB, IP, IF, IHC(P), ELISA
Target: TSPAN8
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-4574
Application*: WB, IF
Target: Tspan8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-5091
Application*: F, IH, MC
Target: Tspan8
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-5090
Application*: F, IH
Target: Tspan8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-5089
Application*: F
Target: TSPAN8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-5088
Application*: F
Target: TSPAN8
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-5086
Application*: WB, F, IC, MC
Target: TSPAN8
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: CBFYC-3212
Application*: E, WB
Target: TSPAN8
Host: Mouse
Antibody Isotype: IgG3, λ
Specificity: Human
Clone: 1E5
Application*: E, WB
Target: TSPAN8
Sensitivity: 0.021 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: TSPAN8
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 106-203
Tag: His Tag
Target: TSPAN8
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 106-203
Tag: His Tag
Target: TSPAN8
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 110-205
Tag: Fc Tag
Target: TSPAN8
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 110-205
Tag: His Tag
Target: TSPAN8
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 110-205
Tag: AVI & His Tag
Target: TSPAN8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D4
Application*: E, F
Target: TSPAN8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3794
Application*: WB, IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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