TXNDC17

TXNDC17 (Thioredoxin Domain Containing 17) is a Protein Coding gene. It is a disulfide reductase. This protein may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. It modulates TNF-alpha signaling and NF-kappa-B activation. It has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Gene Ontology (GO) annotations related to TXNDC17 include electron transfer activity and protein-disulfide reductase activity.

Thioredoxin Domain Containing 17

Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.

Biological Process tumor necrosis factor-mediated signaling pathway Source:UniProtKB1 Publication

Cytoplasm

The oxidized protein is reduced by TRXR1.