TXNDC17
TXNDC17 (Thioredoxin Domain Containing 17) is a Protein Coding gene. It is a disulfide reductase. This protein may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. It modulates TNF-alpha signaling and NF-kappa-B activation. It has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Gene Ontology (GO) annotations related to TXNDC17 include electron transfer activity and protein-disulfide reductase activity.
Full Name
Thioredoxin Domain Containing 17
Function
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
Biological Process
Biological Process tumor necrosis factor-mediated signaling pathway Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
PTM
The oxidized protein is reduced by TRXR1.
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Anti-TXNDC17 antibodies
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Target: TXNDC17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-5460
Application*: WB
Target: TXNDC17
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5459
Application*: E
Target: TXNDC17
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-5458
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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