Rabbit Anti-TXNDC17 Recombinant Antibody (CBYJT-5458) (CBMAB-T5067-YJ)

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Basic Information

Host Animal
Rabbit
Clone
CBYJT-5458
Application
ELISA
Immunogen
Recombinant Human TXNDC17 / TRP14 / TXNL5 protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Thioredoxin Domain Containing 17
Introduction
TXNDC17 (Thioredoxin Domain Containing 17) is a Protein Coding gene. It is a disulfide reductase. This protein may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. It modulates TNF-alpha signaling and NF-kappa-B activation. It has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide. Gene Ontology (GO) annotations related to TXNDC17 include electron transfer activity and protein-disulfide reductase activity.
Entrez Gene ID
UniProt ID
Alternative Names
Thioredoxin Domain Containing 17; Thioredoxin (Trx)-Related Protein, 14 KDa; 14 KDa Thioredoxin-Related Protein; Thioredoxin-Like Protein 5; Thioredoxin-Like 5; Protein 42-9-9
Function
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
Biological Process
Biological Process tumor necrosis factor-mediated signaling pathway Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
PTM
The oxidized protein is reduced by TRXR1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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