VEGFD

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus.
Full Name
Vascular Endothelial Growth Factor D
Function
Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Biological Process
Biological Process dopaminergic neuron differentiation Source:Ensembl
Biological Process fibroblast proliferation Source:Ensembl
Biological Process induction of positive chemotaxis Source:UniProtKB1 Publication
Biological Process positive regulation of angiogenesis Source:GO_Central1 Publication
Biological Process positive regulation of cell division Source:UniProtKB-KW
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of endothelial cell proliferation Source:GO_Central1 Publication
Biological Process positive regulation of mast cell chemotaxis Source:UniProtKB1 Publication
Biological Process positive regulation of protein phosphorylation Source:GO_Central1 Publication
Biological Process response to bacterium Source:Ensembl
Biological Process response to hypoxia Source:GO_Central1 Publication
Biological Process sprouting angiogenesis Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor receptor signaling pathway Source:GO_Central1 Publication
Biological Process vascular endothelial growth factor signaling pathway Source:GO_Central1 Publication
Cellular Location
Secreted
PTM
Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
View more

Anti-VEGFD antibodies

+ Filters
Loading...

Mouse Anti-VEGFD Recombinant Antibody (5D31) (CBMAB-V0085-LY)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 5D31
Application*: WB, P
Datasheet SDS

Rabbit Anti-VEGFD Recombinant Antibody (CBXF-1900) (CBMAB-F3430-CQ)

Go to compareCompare
Target: VEGFD
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1900
Application*: E
Datasheet SDS

Rabbit Anti-VEGFD Recombinant Antibody (CBXF-1899) (CBMAB-F3429-CQ)

Go to compareCompare
Target: VEGFD
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1899
Application*: E
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (CBXF-3643) (CBMAB-F2879-CQ)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3643
Application*: WB
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (CBXF-3607) (CBMAB-F2833-CQ)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3607
Application*: WB, IH
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (CBXF-2531) (CBMAB-F1617-CQ)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2531
Application*: WB
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (CBYY-1407) (CBMAB-1456-YY)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYY-1407
Application*: E, WB
Datasheet SDS

Rat Anti-VEGFD Recombinant Antibody (RM0007-8C35) (CBMAB-V0255-LY)

Go to compareCompare
Target: VEGFD
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: RM0007-8C35
Application*: WB, IH, P
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (MM0007-7E79) (CBMAB-V0195-LY)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: MM0007-7E79
Application*: WB, IH, P
Datasheet SDS

Rat Anti-VEGFD Recombinant Antibody (8C35) (CBMAB-V0099-LY)

Go to compareCompare
Target: VEGFD
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: 8C35
Application*: E, WB
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (3C3) (CBMAB-V0017-LY)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3C3
Application*: WB
Datasheet SDS

Mouse Anti-VEGFD Recombinant Antibody (28AT743.288.48) (CBMAB-V0010-LY)

Go to compareCompare
Target: VEGFD
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 28AT743.288.48
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry