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ZNF136

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms. Alongside CRISPR/Cas9 and TALEN, ZFN is a prominent tool in the field of genome editing.
Full Name
zinc finger protein 136
Function
May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
Biological Process
Biological Process negative regulation of transcription by RNA polymerase II Source:ARUK-UCL1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
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Anti-ZNF136 antibodies

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Mouse Anti-ZNF136 Recombinant Antibody (CBWJZ-162) (CBMAB-Z0344-WJ)

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Target: ZNF136
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJZ-162
Application*: E, EC, IF, WB
Datasheet SDS

Mouse Anti-ZNF136 Recombinant Antibody (ZNF1H5D11) (CBMAB-Z0343-WJ)

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Target: ZNF136
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: ZNF1H5D11
Application*: WB, DB
Datasheet SDS

Mouse Anti-ZNF136 Recombinant Antibody (CBWJZ-114) (CBMAB-Z0342-WJ)

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Target: ZNF136
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJZ-114
Application*: SE, E, WB, IF
Datasheet SDS

Mouse Anti-ZNF136 Recombinant Antibody (5E9) (CBMAB-Z0341-WJ)

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Target: ZNF136
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5E9
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-ZNF136 Recombinant Antibody (8C370) (CBMAB-Z0340-WJ)

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Target: ZNF136
Host: Mouse
Specificity: Human
Clone: 8C370
Application*: WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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