ZSCAN4
ZSCAN4 (Zinc Finger And SCAN Domain Containing 4) is a Protein Coding gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture. Diseases associated with ZSCAN4 include Facioscapulohumeral Muscular Dystrophy 1. Among its related pathways are Preimplantation Embryo.
Full Name
zinc finger and SCAN domain containing 4
Function
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).
Biological Process
Biological Process negative regulation of mitotic recombination Source:BHF-UCLBy Similarity
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process telomere maintenance via telomere lengthening Source:UniProtKB
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process telomere maintenance via telomere lengthening Source:UniProtKB
Cellular Location
Nucleus
Chromosome, telomere
Chromosome, telomere
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Anti-ZSCAN4 antibodies
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Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C7
Application*: SE, E
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D1
Application*: WB
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C5
Application*: WB, IH
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A5
Application*: WB, IH
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E7
Application*: WB
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJZ-107
Application*: SE, E
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5E8
Application*: WB
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3B1
Application*: WB
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A6
Application*: WB, P
Target: ZSCAN4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C6
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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