Mouse Anti-ZSCAN4 Recombinant Antibody (1C6) (CBMAB-Z0770-WJ)

Name: Mouse Anti-ZSCAN4 Recombinant Antibody (1C6)
SKU: CBMAB-Z0770-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1C6

Application

Immunogen

Human recombinant protein fragment corresponding to AA164-433 of human ZSCAN4 (NP_689890) produced in E. coli.

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

More Infomation

Target

Full Name

zinc finger and SCAN domain containing 4

Introduction

ZSCAN4 (Zinc Finger And SCAN Domain Containing 4) is a Protein Coding gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture. Diseases associated with ZSCAN4 include Facioscapulohumeral Muscular Dystrophy 1. Among its related pathways are Preimplantation Embryo.

Entrez Gene ID

201516

UniProt ID

Q8NAM6

Alternative Names

ZNF494

Function

Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).

Biological Process

Biological Process negative regulation of mitotic recombination Source:BHF-UCLBy Similarity
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process telomere maintenance via telomere lengthening Source:UniProtKB

Cellular Location

Nucleus
Chromosome, telomere

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

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