Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

AHI1 Matched Antibody Pair (034) (APMAB-034LY)

Online Inquiry

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-AHI1 polyclonal antibody, 100 ug
Detection Antibody
Anti-AHI1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
Alternative Names
Abelson Helper Integration Site 1; Abelson Helper Integration Site 1 Protein Homolog; Jouberin; AHI-1; Abelson Helper Integration Site; Contatins SH3 And WD40 Domains; DJ71N10.1; JBTS3; ORF1;
Entrez Gene ID
UniProt ID
More Infomation

Hsiao, Y. C., Muñoz-Estrada, J., Tuz, K., & Ferland, R. J. (2021). The transition zone protein AHI1 regulates neuronal ciliary trafficking of MCHR1 and its downstream signaling pathway. Journal of Neuroscience, 41(17), 3932-3943.

Zhang, Q., Hu, Q., Wang, J., Miao, Z., Li, Z., Zhao, Y., ... & Xu, X. (2021). Stress modulates Ahi1-dependent nuclear localization of Ten-Eleven Translocation Protein 2. Human Molecular Genetics.

Sheu, J. J., Yang, L. Y., Sanotra, M. R., Wang, S. T., Lu, H. T., Kam, R. S. Y., ... & Lin, Y. F. (2020). Reduction of AHI1 in the serum of Taiwanese with probable Alzheimer’s disease. Clinical biochemistry, 76, 24-30.

Bourgeois, J. R. (2019). A Role for Abelson Helper Integration Site-1 (AHI1) in Murine Muscular Development and Function Independent of the Central Nervous System (Doctoral dissertation, Albany Medical College).

Ting, L. L., Lu, H. T., Yen, S. F., Ngo, T. H., Tu, F. Y., Tsai, I. S., ... & Lin, Y. F. (2019). Expression of AHI1 rescues amyloidogenic pathology in Alzheimer’s disease model cells. Molecular neurobiology, 56(11), 7572-7582.

Zhu, L., Chen, L., Yan, L., Perkins, B. D., Li, S., Li, B., ... & Li, X. J. (2019). Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Frontiers in cellular neuroscience, 13, 81.

Guo, D., Zhang, S., Sun, H., Xu, X., Hao, Z., Mu, C., ... & Ren, H. (2018). Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice. Journal of Biological Chemistry, 293(14), 5090-5101.

Kaskow, B. J., Buttrick, T. S., Klein, H. U., White, C., Bourgeois, J. R., Ferland, R. J., ... & Elyaman, W. (2018). MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells. Neurology-Neuroimmunology Neuroinflammation, 5(1).

Wolf, G., Lifschytz, T., Ben-Ari, H., Tatarskyy, P., Merzel, T. K., Lotan, A., & Lerer, B. (2018). Effect of chronic unpredictable stress on mice with developmental under-expression of the Ahi1 gene: behavioral manifestations and neurobiological correlates. Translational psychiatry, 8(1), 1-11.

Bozzuto, G., & Molinari, A. (2017). The product of the human AHI-1 (Abelson helper integration site) gene: experimental in vitro data point to its involvement in tumor cell invasion. Annali dell'Istituto superiore di sanita, 53(1), 17-24.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used AHI1 Matched Antibody Pair (034)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry