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ANGPTL3 Matched Antibody Pair (073) (APMAB-073LY)

This antibody pair set can be used for detecting and quantifying protein level of human ANGPTL3.
See all ANGPTL3 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ANGPTL3 monoclonal antibody, 100 ug
Detection Antibody
Anti-ANGPTL3 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]
Alternative Names
Angiopoietin Like 3; Angiopoietin 5; ANGPT5; ANG-5; Angiopoietin-Related Protein 3; Angiopoietin-Like Protein 3;
Entrez Gene ID
27329
UniProt ID
Q9Y5C1

Ling, P., Zheng, X., Luo, S., Ge, J., Xu, S., & Weng, J. (2021). Targeting angiopoietin‐like 3 (ANGPTL3) in atherosclerosis: from bench to bedside. Diabetes, Obesity and Metabolism.

Lu, X. (2020). Structure and function of angiopoietin-like protein 3 (ANGPTL3) in atherosclerosis. Current medicinal chemistry, 27(31), 5159-5174.

Vatannejad, A., Salimi, F., Moradi, N., Fouani, F. Z., Zandieh, Z., Ansaripour, S., ... & Fadaei, R. (2020). Evaluation of angiopoietin-like protein 3 (ANGPTL3) levels in polycystic ovary syndrome. Life Sciences, 263, 118595.

Watts, G. F., Schwabe, C., Scott, R., Gladding, P., Sullivan, D., Baker, J., ... & Ballantyne, C. (2020). RNAi inhibition of angiopoietin-like protein 3 (ANGPTL3) with ARO-ANG3 mimics the lipid and lipoprotein profile of familial combined hypolipidemia. European Heart Journal, 41(Supplement_2), ehaa946-3331.

Adam, R. C., Mintah, I. J., Alexa-Braun, C. A., Shihanian, L. M., Lee, J. S., Banerjee, P., ... & Gusarova, V. (2020). Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance. Journal of lipid research, 61(9), 1271-1286.

Wang, X., & Musunuru, K. (2019). Angiopoietin-like 3: from discovery to therapeutic gene editing. JACC: Basic to Translational Science, 4(6), 755-762.

Tarugi, P., Bertolini, S., & Calandra, S. (2019). Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia. Journal of biomedical research, 33(2), 73.

Lupo, M. G., & Ferri, N. (2018). Angiopoietin-like 3 (ANGPTL3) and atherosclerosis: lipid and non-lipid related effects. Journal of cardiovascular development and disease, 5(3), 39.

Xu, Y. X., Redon, V., Yu, H., Querbes, W., Pirruccello, J., Liebow, A., ... & Kathiresan, S. (2018). Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis, 268, 196-206.

Kersten, S. (2017). Angiopoietin-like 3 in lipoprotein metabolism. Nature Reviews Endocrinology, 13(12), 731-739.

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For research use only. Not intended for any clinical use.

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