ANGPTL3 Matched Antibody Pair (073) (APMAB-073LY)

Name: ANGPTL3 Matched Antibody Pair (073)
SKU: APMAB-073LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-ANGPTL3 monoclonal antibody, 100 ug

Detection Antibody

Anti-ANGPTL3 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

Alternative Names

Angiopoietin Like 3; Angiopoietin 5; ANGPT5; ANG-5; Angiopoietin-Related Protein 3; Angiopoietin-Like Protein 3;

Entrez Gene ID

27329

UniProt ID

Q9Y5C1

More Infomation

Ling, P., Zheng, X., Luo, S., Ge, J., Xu, S., & Weng, J. (2021). Targeting angiopoietin‐like 3 (ANGPTL3) in atherosclerosis: from bench to bedside. Diabetes, Obesity and Metabolism.

Lu, X. (2020). Structure and function of angiopoietin-like protein 3 (ANGPTL3) in atherosclerosis. Current medicinal chemistry, 27(31), 5159-5174.

Vatannejad, A., Salimi, F., Moradi, N., Fouani, F. Z., Zandieh, Z., Ansaripour, S., ... & Fadaei, R. (2020). Evaluation of angiopoietin-like protein 3 (ANGPTL3) levels in polycystic ovary syndrome. Life Sciences, 263, 118595.

Watts, G. F., Schwabe, C., Scott, R., Gladding, P., Sullivan, D., Baker, J., ... & Ballantyne, C. (2020). RNAi inhibition of angiopoietin-like protein 3 (ANGPTL3) with ARO-ANG3 mimics the lipid and lipoprotein profile of familial combined hypolipidemia. European Heart Journal, 41(Supplement_2), ehaa946-3331.

Adam, R. C., Mintah, I. J., Alexa-Braun, C. A., Shihanian, L. M., Lee, J. S., Banerjee, P., ... & Gusarova, V. (2020). Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance. Journal of lipid research, 61(9), 1271-1286.

Wang, X., & Musunuru, K. (2019). Angiopoietin-like 3: from discovery to therapeutic gene editing. JACC: Basic to Translational Science, 4(6), 755-762.

Tarugi, P., Bertolini, S., & Calandra, S. (2019). Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia. Journal of biomedical research, 33(2), 73.

Lupo, M. G., & Ferri, N. (2018). Angiopoietin-like 3 (ANGPTL3) and atherosclerosis: lipid and non-lipid related effects. Journal of cardiovascular development and disease, 5(3), 39.

Xu, Y. X., Redon, V., Yu, H., Querbes, W., Pirruccello, J., Liebow, A., ... & Kathiresan, S. (2018). Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis, 268, 196-206.

Kersten, S. (2017). Angiopoietin-like 3 in lipoprotein metabolism. Nature Reviews Endocrinology, 13(12), 731-739.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant ANGPTL3 protein, His Tag (CAT#: V2LY-0526-LY1373)

Human Recombinant ANGPTL3 protein, His Tag (CAT#: V2LY-0526-LY2117)

Human Recombinant ANGPTL3 protein, His Tag-1 (CAT#: V2LY-0526-LY2118)

Mouse Recombinant ANGPTL3 protein, His Tag (CAT#: V2LY-0526-LY7809)

Mouse Recombinant ANGPTL3 protein, His Tag-1 (CAT#: V2LY-0526-LY7810)

Related Products

Rat Anti-ANGPTL3 Recombinant Antibody (2H44) (CAT#: CBMAB-A2707-YC)

Mouse Recombinant ANGPTL3 protein, His Tag-1 (CAT#: V2LY-0526-LY7810)

Human Recombinant ANGPTL3 protein, His Tag-1 (CAT#: V2LY-0526-LY2118)

Rat Anti-ANGPTL3 Recombinant Antibody (Kairos3-1541) (CAT#: CBMAB-A2713-YC)

Mouse Recombinant ANGPTL3 protein, His Tag (CAT#: V2LY-0526-LY7809)

Human Recombinant ANGPTL3 protein, His Tag (CAT#: V2LY-0526-LY2117)

Mouse Anti-ANGPTL3 Recombinant Antibody (3F11) (CAT#: CBMAB-A2709-YC)

Mouse Anti-ANGPTL3 Recombinant Antibody (Kairos-37) (CAT#: CBMAB-A2715-YC)

Rat Anti-ANGPTL3 Recombinant Antibody (CBYC-A597) (CAT#: CBMAB-A2719-YC)

Mouse Anti-ANGPTL3 Recombinant Antibody (3B7) (CAT#: CBMAB-A2708-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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