Mouse Anti-AAMP Recombinant Antibody (V2-178862) (CBMAB-A0085-YC)

Provided herein is a Mouse monoclonal antibody against Human Angio Associated Migratory Cell Protein. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all AAMP antibodies

Published Data

Fig. 1 Immunohistochemical staining of angio-associated migratory cell protein (AAMP) in human breast tissues.

Fig. 2 Knock-down of AAMP in MCF-7 and MDAMB-231 breast cancer cell lines was confirmed at the protein level, using western blot analysis.

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

V2-178862

Antibody Isotype

IgG2b, κ

Application

ELISA, WB

Basic Information

Immunogen

AAMP (NP_001078.2, 111 a.a. ~ 210 a.a) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.2

Buffer

PBS, pH7.4

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

angio-associated, migratory cell protein

Introduction

AAMP belongs to the immunoglobulin superfamily and is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. AAMP can

Entrez Gene ID

UniProt ID

Q13685

Alternative Names

Angio Associated Migratory Cell Protein;

Function

Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.

Biological Process

Angiogenesis
Cell differentiation
Epidermal growth factor receptor signaling pathway
Nucleotide-binding oligomerization domain containing signaling pathway
Positive regulation of endothelial cell migration
Smooth muscle cell migration
Vascular endothelial growth factor receptor signaling pathway

Cellular Location

Cytoplasm; Cell membrane

References

Yao, S., Shi, F., Mu, N., Li, X., Ma, G., Wang, Y., ... & Su, L. (2021). Angio-associated migratory cell protein (AAMP) interacts with cell division cycle 42 (CDC42) and enhances migration and invasion in human non-small cell lung cancer cells. Cancer Letters, 502, 1-8.

Wang, X., Chen, S., Gao, Y., Yu, C., Nie, Z., Sun, Y., ... & Guan, Z. (2020). MiR-125b is a Potential Protector of Arteriosclerosis Occlusive: Restricting the Proliferation and Migration of Vascular Smooth Muscle Cells via Decreasing the Level of AAMP and SRF.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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