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Mouse Anti-ABCD3 Recombinant Antibody (CL2524) (CBMAB-0003CQ)

This product is a mouse antibody that recognizes ABCD3. The antibody CL2524 can be used for immunoassay techniques such as: IF, IHC-P.
Host Species
Mouse
Application
IF, IHC-P
Immunogen
Human PMP70 aa 410-474
Antibody Isotype
IgG1
Specificity
Human
Clone
CL2524
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. Mutation in ABCD3 have been found in two individuals affected by Zellweger syndrome. However, the role of ABCD3 in the causation of Zellweger syndrome remains uncertain. which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Probable transporter involved in the transport of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial step in bile acid biosynthesis. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
Alternative Name
ATP-Binding Cassette, Sub-Family D (ALD), Member 3; 70 KDa Peroxisomal Membrane Protein; PXMP1; PMP70; DJ824O18.1 (ATP-Binding Cassette, Sub-Family D (ALD), Member 3 (PMP70, PXMP1)); Peroxisomal Membrane Protein 1 (70kD, Zellweger Syndrome); Peroxisomal Membrane Protein-1 (70kD); ABC43; CBAS5; ZWS2
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0003CQ
Conjugates
Size
Price $
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Second antibody and isotype control