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Rabbit Anti-Acetyl-CTNNB1 (Lys49) Recombinant Antibody (D7C2) (CBMAB-CP0135-LY)

The product is antibody recognizes Acetyl-CTNNB1 (Lys49). The antibody D7C2 immunoassay techniques such as: WB,IP.
Host Animal
Rabbit
Application
WB, IP
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic acetylated peptide corresponding to residues surrounding Lys49 of human β-catenin protein.
Antibody Isotype
IgG
Cross Reactivity
Human, Mouse, Monkey
Clone
D7C2
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Alternative Name
EVR7; CTNNB; MRD19; armadillo
Entrez Gene ID
UniProt ID
Cat CBMAB-CP0135-LY
Conjugates
Size
Price $
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