Rabbit Anti-ACO2 Recombinant Antibody (
8H4) (V2LY-0725-LY1062)

Palmieri, E. M., Gonzalez-Cotto, M., Baseler, W. A., Davies, L. C., Ghesquière, B., Maio, N., ... & McVicar, D. W. (2020). Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase. Nature communications, 11(1), 1-17.

Ciccarone, F., Di Leo, L., Lazzarino, G., Maulucci, G., Di Giacinto, F., Tavazzi, B., & Ciriolo, M. R. (2020). Aconitase 2 inhibits the proliferation of MCF-7 cells promoting mitochondrial oxidative metabolism and ROS/FoxO1-mediated autophagic response. British journal of cancer, 122(2), 182-193.

Ciccarone, F., De Falco, P., & Ciriolo, M. R. (2020). Aconitase 2 sensitizes MCF-7 cells to cisplatin eliciting p53-mediated apoptosis in a ROS-dependent manner. Biochemical Pharmacology, 180, 114202.

Fukada, M., Yamada, K., Eda, S., Inoue, K., Ohba, C., Matsumoto, N., ... & Nakayama, A. (2019). Identification of novel compound heterozygous mutations in ACO2 in a patient with progressive cerebral and cerebellar atrophy. Molecular genetics & genomic medicine, 7(7), e00698.

Marelli, C., Hamel, C., Quiles, M., Carlander, B., Larrieu, L., Delettre, C., ... & Guissart, C. (2018). ACO2 mutations: A novel phenotype associating severe optic atrophy and spastic paraplegia. Neurology Genetics, 4(2).

Kelman, J. C., Kamien, B. A., Murray, N. C., Goel, H., Fraser, C. L., & Grigg, J. R. (2018). A sibling study of isolated optic neuropathy associated with novel variants in the ACO2 gene. Ophthalmic genetics, 39(5), 648-651.

Bouwkamp, C. G., Afawi, Z., Fattal-Valevski, A., Krabbendam, I. E., Rivetti, S., Masalha, R., ... & Kushner, S. A. (2018). ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia. Neurology Genetics, 4(2).

Abela, L., Spiegel, R., Crowther, L. M., Klein, A., Steindl, K., Papuc, S. M., ... & Simmons, T. L. (2017). Plasma metabolomics reveals a diagnostic metabolic fingerprint for mitochondrial aconitase (ACO2) deficiency. PloS one, 12(5), e0176363.

Srivastava, S., Gubbels, C. S., Dies, K., Fulton, A., Yu, T., & Sahin, M. (2017). Increased survival and partly preserved cognition in a patient with ACO2-related disease secondary to a novel variant. Journal of child neurology, 32(9), 840-845.

Chen, C. M., Wu, Y. R., & Chang, K. H. (2017). Altered aconitase 2 activity in Huntington’s disease peripheral blood cells and mouse model striatum. International journal of molecular sciences, 18(11), 2480.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols