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Mouse Anti-ADAM10 Recombinant Antibody (11G2) (CBMAB-0024CQ)

This product is a mouse antibody that recognizes ADAM10. The antibody 11G2 can be used for immunoassay techniques such as: WB, FC, IHC-P, IP.
Host Species
Mouse
Application
WB, FC, IHC-P, IP
Application Notes
This 11G2 antibody has been reported in applications of WB, IF, IHC, FCM.

For western blot, the recommended concentration is 1:200, and predicted molecular weight is 84 KDa.

For IHC and IF, the recommended concentration is 5 µg/ml. Before IHC staining, a kindly reminder that please conduct heat mediated antigen retrieval with citrate buffer before commencing. (Buffer: pH 6)

For flow cytometry, the reported concentration is for your reference: 10 µg/ml FITC-conjugated 11G2 mAb was used to stain 1*10^5 cells.

It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated and determined by the end user.
Antibody Isotype
IgG1
Specificity
Human
Clone
11G2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The ADAM10 gene encodes a member of the ADAM (a disintegrin and metalloprotease) family and possesses alpha-secretase activity. Tumor necrosis factor-alpha (TNFA) is synthesized as a proinflammatory cytokine from a 233-amino acid precursor. Conversion of the membrane-bound precursor to a secreted mature protein is mediated by a protease termed TNFA convertase. Lunn et al. (1997) found that ADAM10 possesses TNFA convertase activity.
Alternative Name
ADAM Metallopeptidase Domain 10; Mammalian Disintegrin-Metalloprotease; Kuzbanian Protein Homolog; EC 3.4.24.81; CDw156; MADM; Kuz; A Disintegrin And Metalloproteinase Domain 10; A Disintegrin And Metalloprotease Domain 10; CD156c Antigen; EC 3.4.24; HsT18717; ADAM 10; CD156c; AD10; AD18; RAK
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0024CQ
Conjugates
Size
Price $
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Second antibody and isotype control