Mouse Anti-ADAM29 Recombinant Antibody (V2-179786) (CBMAB-A1148-YC)

Provided herein is a Mouse monoclonal antibody against Human ADAM Metallopeptidase Domain 29. The antibody can be used for immunoassay techniques, such as ELISA.
See all ADAM29 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

V2-179786

Antibody Isotype

IgM, κ

Application

ELISA

Basic Information

Immunogen

ADAM29 (NP_055084, 339-398 aa) partial recombinant protein with GST tag. Immunogen sequence: GMNHDEDTCR CSQPRCIMHE GNPPITKFSN CSYGDFWEYT VERTKCLLET VHTKDIFNVK

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgM, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Ascites

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 339-398

Target

Full Name

ADAM metallopeptidase domain 29

Introduction

ADAM29 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involvi

Entrez Gene ID

11086

UniProt ID

Q9UKF5

Alternative Names

ADAM Metallopeptidase Domain 29; Cancer/Testis Antigen 73; A Disintegrin And Metalloproteinase Domain 29; CT73; Disintegrin And Metalloproteinase Domain-Containing Protein 29; Testis Secretory Sperm-Binding Protein Li 207a;

Function

May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.

Biological Process

Male gonad development
Spermatogenesis

Cellular Location

Membrane

Topology

Extracellular: 194-674 aa
Helical: 675-695 aa
Cytoplasmic: 696-820 aa

References

Wang, T., Lv, X., Jiang, S., Han, S., & Wang, Y. (2020). Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance. Oncology letters, 19(3), 1727-1734.

Li, S. L., Jiang, T. Q., Cao, Q. W., & Liu, S. M. (2020). Transmembrane protein ADAM29 facilitates cell proliferation, invasion and migration in clear cell renal cell carcinoma. Journal of Chemotherapy, 33(1), 40-50.

Wang, L., Hoggard, J. A., Korleski, E. D., Long, G. V., Ree, B. C., Hensley, K., ... & Bridges, L. C. (2018). Multiple non-catalytic ADAMs are novel integrin α4 ligands. Molecular and cellular biochemistry, 442(1), 29-38.

Chen, H., & Wang, S. (2018). Clinical significance of ADAM29 promoting the invasion and growth of gastric cancer cells in vitro. Oncology letters, 16(2), 1483-1490.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-ADAM29 Recombinant Antibody (V2-179787)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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