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Mouse Anti-ADAM30 Recombinant Antibody (V2-179789) (CBMAB-A1151-YC)

Provided herein is a Mouse monoclonal antibody against Human ADAM Metallopeptidase Domain 30. The antibody can be used for immunoassay techniques, such as ELISA.
See all ADAM30 antibodies
Published Data
Fig.1 Northern blot analysis.
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Fig.2 Characterization of ADAM30 expression in the brain.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-179789
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa199-299 from human ADAM30 (NP_068566) with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid in PBS, pH 7.2
Buffer
PBS, pH7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ADAM metallopeptidase domain 30
Introduction
ADAM30 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involvi
Entrez Gene ID
11085
UniProt ID
Q9UKF2
Alternative Names
ADAM Metallopeptidase Domain 30; A Disintegrin And Metalloproteinase Domain 30; Disintegrin And Metalloproteinase Domain-Containing Protein 30; EC 3.4.24.-; ADAM 30; Svph4;
Function
Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.
Biological Process
Binding of sperm to zona pellucida
Cellular Location
Late endosome membrane
Topology
Extracellular: 199-687 aa
Helical: 688-708 aa
Cytoplasmic: 709-790 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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