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Mouse Anti-ADAP2 Recombinant Antibody (V2-362972) (CBMAB-C5777-CQ)

This product is a mouse antibody that recognizes ADAP2. The antibody CBXC-1784 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all ADAP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-362972
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Raised against amino acids 271-381 mapping at the C-terminus of Centaurin α2 of human origin.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate).
IF(ICC)1:50-1:500
ELISA1:30-1:3,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, 0.1% gelatin.
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ArfGAP With Dual PH Domains 2
Introduction
The protein encoded by this gene binds beta-tubulin and increases the stability of microtubules. The encoded protein can also translocate to the cell membrane and bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). In addition, this protein is a GTPase-activating protein for ADP ribosylation factor 6 and may be able to block the entry of some RNA viruses.
Entrez Gene ID
55803
UniProt ID
Q9NPF8
Alternative Names
ArfGAP With Dual PH Domains 2; CENTA2; Arf-GAP With Dual PH Domain-Containing Protein 2; Centaurin-Alpha 2 Protein; Centaurin, Alpha 2; Centaurin-Alpha-2;
Function
GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity.
Biological Process
Heart development
Inositol lipid-mediated signaling
Cellular Location
Cytoplasm; Cell membrane. Constitutively associated with the plasma membrane. Excluded from the nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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