Mouse Anti-ADH7 Recombinant Antibody (V2-179911) (CBMAB-A1295-YC)

Name: Mouse Anti-ADH7 Recombinant Antibody (V2-179911)
SKU: CBMAB-A1295-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

V2-179911

Application

IHC-F, WB

Immunogen

Full length human recombinant protein of human ADH7(NP_000664) produced in HEK293T cell

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:2,000
FC	1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide

Introduction

ADH7 is class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and

Entrez Gene ID

131

UniProt ID

P40394

Alternative Names

Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide; Alcohol Dehydrogenase Class IV Mu/Sigma Chain; Gastric Alcohol Dehydrogenase; Retinol Dehydrogenase; EC 1.1.1.1; Alcohol Dehydrogenase Class 4 Mu/Sigma Chain; Class IV Sigmasigma Alcohol Dehydro

Function

Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.

Biological Process

Ethanol catabolic process
Ethanol oxidation
Fatty acid omega-oxidation
Response to bacterium
Response to ethanol
Retinoic acid metabolic process
Retinoid metabolic process
Retinol metabolic process

Cellular Location

Cytoplasm

Suo, C., Yang, Y., Yuan, Z., Zhang, T., Yang, X., Qing, T., ... & Ye, W. (2019). Alcohol intake interacts with functional genetic polymorphisms of aldehyde dehydrogenase (ALDH2) and alcohol dehydrogenase (ADH) to increase esophageal squamous cell cancer risk. Journal of Thoracic Oncology, 14(4), 712-725.

Guo, E., Wei, H., Liao, X., Xu, Y., Li, S., & Zeng, X. (2018). Prognostic value of alcohol dehydrogenase mRNA expression in gastric cancer. Oncology letters, 15(4), 5505-5516.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

ADH7 Matched Antibody Pair (028) (CAT#: APMAB-028LY)

Related Products

Mouse Anti-ADH7 Recombinant Antibody (V2-179913) (CAT#: CBMAB-A1297-YC)

Mouse Anti-ADH7 Recombinant Antibody (V2-179912) (CAT#: CBMAB-A1296-YC)

ADH7 Matched Antibody Pair (028) (CAT#: APMAB-028LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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