How specific is this antibody? Does it cross-react with other common adenovirus serotypes like Ad2 or Ad5?

This antibody was generated using recombinant Adenovirus serotype 1 (Ad1) hexon protein as the immunogen and is validated to be highly specific for Ad1. In our internal testing, we have not observed significant cross-reactivity with the hexon proteins of other common serotypes like Ad2 and Ad5 in standard applications like ELISA and IF. It is an excellent tool for studies requiring serotype-specific detection.

Can I use this antibody for functional assays, such as neutralizing Ad1 infectivity?

This antibody is a high-performance reagent specifically validated for detection applications (ELISA, WB, IF). It has not been tested or qualified for its ability to neutralize Ad1 infectivity in cell culture. Functional characterization for neutralization would require independent validation by the end-user.

Mouse Anti-ADV-1 Hexon Recombinant Antibody (V2-503459) (CBMAB-V208-1431-FY)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

V2-503459

Application

ELISA, IHC, IF

Immunogen

Hexon antigen of human and canine adenoviruses (Type 1).

Host Species

Mouse

Specificity

ADV

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH7.4

Preservative

0.09% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Adenovirus-1

Introduction

Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.

Alternative Names

ADV-1; Adenovirus-1

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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