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Mouse Anti-AGR3 Recombinant Antibody (V2-180207) (CBMAB-A1633-YC)

Provided herein is a Mouse monoclonal antibody against Human Anterior Gradient 3, Protein Disulphide Isomerase Family Member. The antibody can be used for immunoassay techniques, such as ICC, IF, IHC-Fr, IHC-P, WB.
See all AGR3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-180207
Antibody Isotype
IgG1
Application
ICC, IF, IHC-P, WB

Basic Information

Immunogen
Purified human AGR3 protein
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1 μg/ml
IF(ICC)1 μg/ml
IHC-P1 μg/ml
IHC-F1 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Preservative
15 mM sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Anterior Gradient 3, Protein Disulphide Isomerase Family Member
Introduction
AGR3 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thior
Entrez Gene ID
155465
UniProt ID
Q8TD06
Alternative Names
Anterior Gradient 3, Protein Disulphide Isomerase Family Member; Protein Disulfide Isomerase Family A, Member 18; Breast Cancer Membrane Protein 11; BCMP11; PDIA18; HAG-3; AG-3; AG3;
Function
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Biological Process
Negative regulation of cell death
Cellular Location
Endoplasmic reticulum. Found in the cytoplasm, which could include the endoplasmic reticulum.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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