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Rabbit Anti-APBA2 Recombinant Antibody (D8A6) (CBMAB-A3015-YC)

Provided herein is a Rabbit monoclonal antibody against Human Amyloid Beta Precursor Protein Binding Family A Member 2. The antibody can be used for immunoassay techniques, such as WB, IP.
See all APBA2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
D8A6
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Synthetic peptide corresponding to residues surrounding Val23 of human APBA2 protein.
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000
IP1:50

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, pH 7.5, 150 mM NaCl, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Amyloid Beta Precursor Protein Binding Family A Member 2
Introduction
APBA2 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide
Entrez Gene ID
Human321
Mouse11784
Rat83610
UniProt ID
HumanQ99767
MouseP98084
RatO35431
Alternative Names
Amyloid Beta Precursor Protein Binding Family A Member 2; Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 2 (X11-Like); Neuronal Munc18-1-Interacting Protein 2; Neuron-Specific X11L Protein; Adapter Protein X11beta; Mint-2; MINT2; X11L; Phos
Function
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.
Biological Process
Chemical synaptic transmission Source: GO_Central
Nervous system development Source: ProtInc
Protein transport Source: UniProtKB-KW
Cellular Location
Plasma membrane; Cytoplasm; Dendritic spine; Synaptic vesicle
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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