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Mouse Anti-APBB3 Recombinant Antibody (1G5) (CBMAB-A3021-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1G5
Antibody Isotype
IgG1
Application
FC, WB

Basic Information

Immunogen
Full length human recombinant protein of human APBB3(NP_573419) produced in HEK293T cell
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Amyloid Beta Precursor Protein Binding Family B Member 3
Introduction
APBB3 is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. APBB3 may modulate the internalization
Entrez Gene ID
10307
UniProt ID
O95704
Alternative Names
Amyloid Beta Precursor Protein Binding Family B Member 3; Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 3; Protein Fe65-Like 2; FE65L2; Amyloid-Beta A4 Precursor Protein-Binding Family B Member 3; Amyloid Precursor Interacting Protein; FE6
Function
May modulate the internalization of amyloid-beta precursor protein.
Biological Process
Positive regulation of protein secretion Source: ARUK-UCL
Regulation of transcription, DNA-templated Source: GO_Central
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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