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Mouse Anti-APOBEC2 Recombinant Antibody (4D7) (CBMAB-A3173-YC)

Provided herein is a Mouse monoclonal antibody against Human Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 2. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all APOBEC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4D7
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
APOBEC2 (NP_006780. 1, 1-224 aa) full-length recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-224

Target

Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
Introduction
APOBEC2 is a probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression thr
Entrez Gene ID
10930
UniProt ID
Q9Y235
Alternative Names
Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 2; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 2; MRNA(Cytosine(6666)) Deaminase 2; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 2; Probable C->U-Editing Enzyme APO
Function
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Biological Process
Cytidine to uridine editing Source: MGI
DNA demethylation Source: UniProtKB
mRNA modification Source: Ensembl
mRNA processing Source: UniProtKB-KW
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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