Mouse Anti-APOBEC2 Recombinant Antibody (4D7) (CBMAB-A3173-YC)

Name: Mouse Anti-APOBEC2 Recombinant Antibody (4D7)
SKU: CBMAB-A3173-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

4D7

Application

ELISA, WB

Immunogen

APOBEC2 (NP_006780. 1, 1-224 aa) full-length recombinant protein with GST tag.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-224

More Infomation

Target

Full Name

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2

Introduction

APOBEC2 is a probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression thr

Entrez Gene ID

10930

UniProt ID

Q9Y235

Alternative Names

Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 2; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 2; MRNA(Cytosine(6666)) Deaminase 2; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide 2; Probable C->U-Editing Enzyme APO

Function

Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Biological Process

Cytidine to uridine editing Source: MGI
DNA demethylation Source: UniProtKB
mRNA modification Source: Ensembl
mRNA processing Source: UniProtKB-KW

Cellular Location

Nucleus; Cytoplasm

Li, A., Wu, J., Zhai, A., Qian, J., Wang, X., Qaria, M. A., ... & Zhang, F. (2019). HBV triggers APOBEC2 expression through miR‑122 regulation and affects the proliferation of liver cancer cells. International journal of oncology, 55(5), 1137-1148.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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