Mouse Anti-APOL2 Recombinant Antibody (D4) (CBMAB-AP398LY)

See all APOL2 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

Antibody Isotype

IgG1, κ

Application

WB, IHC, IF

Basic Information

Immunogen

Recombinant protein Apolipoprotein L2. The antigen corresponds to amino acid range 186-337 of the target protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	0.5-5 µg/ml
IF(ICC)	5-30 µg/ml
IHC-P	5-30 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 50% glycerol

Preservative

0.05% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Apolipoprotein L2

Introduction

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Entrez Gene ID

23780

UniProt ID

Q9BQE5

Alternative Names

Apolipoprotein L2; Apolipoprotein L-II; APOL-II; Apolipoprotein L, 2; APOL3;

Function

May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.

Biological Process

Acute-phase response Source: UniProtKB
Cholesterol metabolic process Source: UniProtKB
Lipid metabolic process Source: UniProtKB
Lipid transport Source: UniProtKB
Lipoprotein metabolic process Source: InterPro
Maternal process involved in female pregnancy Source: UniProtKB
Multicellular organism development Source: UniProtKB

Cellular Location

Cytoplasm

References

Ultsch, M., Holliday, M. J., Gerhardy, S., Moran, P., Scales, S. J., Gupta, N., ... & Kirchhofer, D. (2021). Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif. Communications Biology, 4(1), 1-16.

Luo, A., Jung, J., Longley, M., Rosoff, D. B., Charlet, K., Muench, C., ... & Lohoff, F. W. (2020). Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2. Neuropsychopharmacology, 45(2), 327-336.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

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Datasheet
SDS
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Second antibody and isotype control

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