Rabbit Anti-ARID3B Recombinant Antibody (CBYC-A768) (CBMAB-A3554-YC)

Name: Rabbit Anti-ARID3B Recombinant Antibody (CBYC-A768)
SKU: CBMAB-A3554-YC
Rating: 5 (1 reviews)

See all ARID3B antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBYC-A768

Application

Immunogen

A synthetic peptide corresponding to the center region of the Human ARID3B

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

AT-Rich Interaction Domain 3B

Introduction

ARID3B is a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer protein

Entrez Gene ID

10620

UniProt ID

Q8IVW6

Alternative Names

AT-Rich Interaction Domain 3B; AT Rich Interactive Domain 3B (BRIGHT- Like); ARID Domain-Containing Protein 3B; Bright And Dead Ringer Protein; Bright-Like Protein; DRIL2; BDP; AT-Rich Interactive Domain-Containing Protein 3B; AT Rich Interactive Domain 3

Function

Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.

Biological Process

Positive regulation of transcription by RNA polymerase II Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

Saadat, K. A., Lestari, W., Pratama, E., Ma, T., Iseki, S., Tatsumi, M., & Ikeda, M. A. (2021). Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes. International Journal of Oncology, 58(4), 1-12.

Liao, T. T., Lin, C. C., Jiang, J. K., Yang, S. H., Teng, H. W., & Yang, M. H. (2020). Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer. Theranostics, 10(14), 6095.

Ali, A., Bouma, G. J., Anthony, R. V., & Winger, Q. A. (2020). The role of LIN28-let-7-ARID3B pathway in placental development. International Journal of Molecular Sciences, 21(10), 3637.

Ali, A., Anthony, R. V., Bouma, G. J., & Winger, Q. A. (2019). LIN28‐let‐7 axis regulates genes in immortalized human trophoblast cells by targeting the ARID3B‐complex. The FASEB Journal, 33(11), 12348-12363.

Nakahara, S., Fukushima, S., Yamashita, J., Kubo, Y., Tokuzumi, A., Miyashita, A., ... & Ihn, H. (2017). AT-rich interaction domain-containing protein 3B is a new tumour marker for melanoma. Acta dermato-venereologica, 97(1), 112-114.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-ARID3B Recombinant Antibody (CBYC-A768)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-ARID3B Recombinant Antibody (C-6) (CAT#: CBMAB-A3553-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry