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Mouse Anti-ARL4A Recombinant Antibody (CBYC-A777) (CBMAB-A3597-YC)

Provided herein is a Rabbit monoclonal antibody against Human ADP Ribosylation Factor Like GTPase 4A. The antibody can be used for immunoassay techniques, such as WB.
See all ARL4A antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Cattle, Pig, Dog
Clone
CBYC-A777
Antibody Isotype
IgG2a, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 137-196 mapping near the C-terminus of ARL4 of human origin.
Specificity
Human, Mouse, Rat, Cattle, Pig, Dog
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ADP Ribosylation Factor Like GTPase 4A
Introduction
ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is lo
Entrez Gene ID
UniProt ID
Alternative Names
ADP Ribosylation Factor Like GTPase 4A; ADP-Ribosylation Factor-Like 4A; ADP-Ribosylation Factor-Like 4; ARL4; ADP-Ribosylation Factor-Like Protein 4A;
Function
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.
Biological Process
Brown fat cell differentiation Source: Ensembl
Intracellular protein transport Source: GO_Central
Vesicle-mediated transport Source: GO_Central
Cellular Location
Cytoplasm; Nucleolus; Cell membrane. Localization in the nucleolus is dependent by nucleotide binding.
PTM
Myristoylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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