Sign in or Register   Sign in or Register
  |  

Mouse Anti-ASB5 Recombinant Antibody (6B10) (CBMAB-A0527-LY)

The product is antibody recognizes ASB5. The antibody 6B10 immunoassay techniques such as: WB, ELISA.
See all ASB5 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
6B10
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
ASB5 (NP_543150, 220 a.a. ~ 328 a.a) partial recombinant protein with GST tag.
Specificity
Human, Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ankyrin repeat and SOCS box-containing 5
Introduction
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq]
Entrez Gene ID
Human140458
Mouse76294
UniProt ID
HumanQ8WWX0
MouseQ9D1A4
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity).
Biological Process
Intracellular signal transduction Source: InterPro
Positive regulation of protein catabolic process Source: GO_Central
Post-translational protein modification Source: Reactome
Protein ubiquitination Source: GO_Central
Cellular Location
Cytosol
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-ASB5 Recombinant Antibody (6B10)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare