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Mouse Anti-ASRGL1 Recombinant Antibody (CRASH/1289) (CBMAB-1153-CN)

This product is a mouse antibody that recognizes ASRGL1 of human. The antibody CRASH/1289 can be used for immunoassay techniques such as: IHC-P.
See all ASRGL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CRASH/1289
Antibody Isotype
IgG1
Application
IHC-P

Basic Information

Immunogen
Recombinant human ASRGL1 fragment.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IHC-P1-2 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.05% BSA
Preservative
0.05% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Asparaginase Like 1
Introduction
ASRGL1 acts in asparagine catabolism. This protein may be involved in astroglial production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions.
Entrez Gene ID
80150
UniProt ID
Q7L266
Alternative Names
ALP; ALP1; CRASH
Function
Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.
Biological Process
Asparagine catabolic process via L-aspartate Source: UniProtKB
L-phenylalanine metabolic process Source: Reactome
Cellular Location
Cytoplasm. Midpiece of sperm tail.
PTM
Cleaved into an alpha and beta chain by autocatalysis; this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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