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Mouse Anti-ATP6V1D Recombinant Antibody (3G4) (CBMAB-A4100-YC)

Provided herein is a Mouse monoclonal antibody against Human ATPase H+ Transporting V1 Subunit D. The antibody can be used for immunoassay techniques, such as ELISA, IHC-P, WB.
See all ATP6V1D antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G4
Antibody Isotype
IgG2a
Application
ELISA, IHC-P, WB

Basic Information

Immunogen
Recombinant protein, ATP6V1D (NP_057078, 69-169 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IHC-P3 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 69-169

Target

Full Name
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
Introduction
ATP6V1D is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zy
Entrez Gene ID
51382
UniProt ID
Q9Y5K8
Alternative Names
ATPase H+ Transporting V1 Subunit D; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump); ATPase, H+ Transporting, Lysosomal 34kDa, V1 Subunit D; V-ATPase 28 KDa Accessory Protein; Vacuolar Proton Pump Subunit D; V-ATPase Subunit D; ATP6M; VATD; H(+
Function
Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).
May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.
Biological Process
Cellular response to amino acid starvation Source: Reactome
Cilium assembly Source: UniProtKB
Insulin receptor signaling pathway Source: Reactome
Ion transmembrane transport Source: Reactome
Neutrophil degranulation Source: Reactome
Phagosome acidification Source: Reactome
Protein localization to cilium Source: UniProtKB
Regulation of macroautophagy Source: ParkinsonsUK-UCL
Transferrin transport Source: Reactome
Cellular Location
Membrane. Localizes to centrosome and the base of the cilium.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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