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Mouse Anti-ATP6V1G2 Recombinant Antibody (2E11) (CBMAB-A4107-YC)

Provided herein is a Mouse monoclonal antibody against Human ATPase H+ Transporting V1 Subunit G2. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all ATP6V1G2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E11
Antibody Isotype
IgG2b, λ
Application
ELISA, WB

Basic Information

Immunogen
ATP6V1G2 (NP_569730, 41-118 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2b, λ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 41-118

Target

Full Name
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
Introduction
ATP6V1G2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting,
Entrez Gene ID
UniProt ID
Alternative Names
ATPase H+ Transporting V1 Subunit G2; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump); ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2; V-ATPase 13 KDa Subunit 2; ATP6G2; ATP6G; NG38; ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit
Function
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Biological Process
Cellular response to amino acid starvation Source: Reactome
Insulin receptor signaling pathway Source: Reactome
Ion transmembrane transport Source: Reactome
Phagosome acidification Source: Reactome
Proton transmembrane transport Source: InterPro
Regulation of macroautophagy Source: ParkinsonsUK-UCL
Transferrin transport Source: Reactome
Cellular Location
Melanosome. Highly enriched in late-stage melanosomes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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