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Mouse Anti-AXUD1 Recombinant Antibody (5E8) (CBMAB-A0675-LY)

The product is antibody recognizes AXUD1. The antibody 5E8 immunoassay techniques such as: WB, ELISA.
See all AXUD1 antibodies
Published Data
Fig.1 Elevated expression of AXUD1 in LoVo cells in response to Ad-Axin.
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Fig.2 Immunocytochemical staining of ¯ag-tagged AXUD1 protein.
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Fig.3 Axud1 Is a Marker of the Premigratory Neural Crest in Chick Embryos.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
5E8
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
AXUD1 (AAH38949, 1 a.a. ~ 589 a.a) full-length recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
AXIN1 up-regulated 1
Introduction
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq]
Entrez Gene ID
64651
UniProt ID
Q96S65
Alternative Names
CSRNP1; DKFZp566F164; FAM130B; TAIP-3; URAX1
Function
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity).
May have a tumor-suppressor function. May play a role in apoptosis.
Biological Process
Apoptotic process Source: UniProtKB
Face morphogenesis Source: Ensembl
Platelet-derived growth factor receptor signaling pathway Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Post-embryonic development Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Roof of mouth development Source: Ensembl
Skeletal system morphogenesis Source: Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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