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Mouse Anti-B3GALT2 Recombinant Antibody (1D9) (CBMAB-A0682-LY)

The product is antibody recognizes B3GALT2. The antibody 1D9 immunoassay techniques such as: sELISA, ELISA.
See all B3GALT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D9
Antibody Isotype
IgG2a, κ
Application
IF, ELISA

Basic Information

Immunogen
B3GALT2 (NP_003774, 324 a.a. ~ 422 a.a) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IF(ICC)10 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Introduction
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq]
Entrez Gene ID
8707
UniProt ID
O43825
Alternative Names
BETA3GALT2; GLCT2; beta3Gal-T2
Function
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Biological Process
Galactosylceramide biosynthetic process Source: BHF-UCL
Oligosaccharide biosynthetic process Source: Reactome
Poly-N-acetyllactosamine biosynthetic process Source: GO_Central
Protein glycosylation Source: GO_Central
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-24 aa
Helical: 25-45 aa
Lumenal: 46-422 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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