Sign in or Register   Sign in or Register
  |  

Mouse Anti-BAALC (N-terminus) Recombinant Antibody (CBYY-0103) (CBMAB-0103-YY)

This product is mouse antibody that recognizes BAALC. The antibody CBYY-0103 can be used for immunoassay techniques such as: WB, IP, ICC
See all BAALC antibodies
Published Data
Mouse Anti-BAALC (N-terminus) Recombinant Antibody (CBYY-0103) in WB
Western blotting of BAALC protein expression in CD34+ cells derived from HD, CN, and CN/AML iPSCs. Numbers indicate protein expression levels normalized to b-actin and shown relative to HD. ...View More
Dannenmann, B., Klimiankou, M., Oswald, B., Solovyeva, A., Mardan, J., Nasri, M., ... & Skokowa, J. (2021). iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia. Cell Stem Cell, 28(5), 906-922.

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-0103
Antibody Isotype
IgG2b, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 39-56 within an internal region of BAALC of human origin.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
N-terminus

Target

Full Name
brain and acute leukemia, cytoplasmic
Introduction
This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisMouse. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines.
Entrez Gene ID
79870
UniProt ID
Q8WXS3
Alternative Names
BAALC, MAP3K1 And KLF4 Binding; Brain And Acute Leukemia, Cytoplasmic; BAALC, MEKK1 And KLF4 Binding;
Function
May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A.
Cellular Location
Cytoplasm; Synaptosome; Membrane raft; Postsynaptic density. In neurons, localizes to postsynaptic lipid rafts (By similarity). In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity).
PTM
Palmitoylation and myristoylation target the protein to the lipid rafts.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-BAALC (N-terminus) Recombinant Antibody (CBYY-0103)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare