Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287) (CBMAB-0288-YY)

Name: Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287)
SKU: CBMAB-0288-YY
Rating: 5 (1 reviews)

See all BCAS1 antibodies

Compare Online Inquiry

Published Data

Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287) (CBMAB-0288-YY) in IF

Representative longitudinal lumbosacral spinal cord sections triple-immunolabeled for GFP (green), BrdU (cyan) along with BCAS1 and Olig2 (red), respectively. Cell nuclei were counterstained with DAPI (blue). Scale bar = 50 μm. ...View More

Theotokis, P., Kesidou, E., Mitsiadou, D., Petratos, S., Damianidou, O., Boziki, M., ... & Grigoriadis, N. (2022). Lumbar spine intrathecal transplantation of neural precursor cells promotes oligodendrocyte proliferation in hot spots of chronic demyelination. Brain Pathology, 32(4), e13040.

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-0287

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 1-300 mapping at the N-terminus of NaBC1 of human origin.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.2 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

breast carcinoma amplified sequence 1

Introduction

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]

Entrez Gene ID

8537

UniProt ID

O75363

Alternative Names

Breast Carcinoma Amplified Sequence 1; Amplified And Overexpressed In Breast Cancer; Novel Amplified In Breast Cancer 1; AIBC1; NABC1; Breast Carcinoma-Amplified Sequence 1;

Function

Required for myelination.

Biological Process

Myelination Source: UniProtKB

Cellular Location

Cytoplasm

Ulloa-Navas, M. J., Rubio, L., Teruel-Sanchis, A., Peña-Peña, J., García-Verdugo, J. M., Herranz-Pérez, V., & Ferrer-Lozano, J. (2021). Heterogeneous Pattern of Differentiation With BCAS1/NABC1 Expression in a Case of Oligodendroglioma. Journal of Neuropathology & Experimental Neurology, 80(4), 379-383.

Fard, M. K., Van Der Meer, F., Sánchez, P., Cantuti-Castelvetri, L., Mandad, S., Jäkel, S., ... & Simons, M. (2017). BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science translational medicine, 9(419).

Ishimoto, T., Ninomiya, K., Inoue, R., Koike, M., Uchiyama, Y., & Mori, H. (2017). Mice lacking BCAS1, a novel myelin‐associated protein, display hypomyelination, schizophrenia‐like abnormal behaviors, and upregulation of inflammatory genes in the brain. Glia, 65(5), 727-739.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-BCAS1 Recombinant Antibody (CBYY-1895) (CAT#: CBMAB-2244-YY)

Mouse Anti-BCAS1 Recombinant Antibody (1B5) (CAT#: CBMAB-A0727-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry