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Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287) (CBMAB-0288-YY)

This product is mouse antibody that recognizes BCAS1. The antibody CBYY-0287 can be used for immunoassay techniques such as: ELISA, WB, IHC
See all BCAS1 antibodies
Published Data
Mouse Anti-BCAS1 Recombinant Antibody (CBYY-0287) (CBMAB-0288-YY) in IF
Representative longitudinal lumbosacral spinal cord sections triple-immunolabeled for GFP (green), BrdU (cyan) along with BCAS1 and Olig2 (red), respectively. Cell nuclei were counterstained with DAPI (blue). Scale bar = 50 μm. ...View More
Theotokis, P., Kesidou, E., Mitsiadou, D., Petratos, S., Damianidou, O., Boziki, M., ... & Grigoriadis, N. (2022). Lumbar spine intrathecal transplantation of neural precursor cells promotes oligodendrocyte proliferation in hot spots of chronic demyelination. Brain Pathology, 32(4), e13040.

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-0287
Antibody Isotype
IgG2a, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 1-300 mapping at the N-terminus of NaBC1 of human origin.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
breast carcinoma amplified sequence 1
Introduction
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]
Entrez Gene ID
8537
UniProt ID
O75363
Alternative Names
Breast Carcinoma Amplified Sequence 1; Amplified And Overexpressed In Breast Cancer; Novel Amplified In Breast Cancer 1; AIBC1; NABC1; Breast Carcinoma-Amplified Sequence 1;
Function
Required for myelination.
Biological Process
Myelination Source: UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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