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Mouse Anti-BNIP2 Recombinant Antibody (8C6) (CBMAB-A0843-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
8C6
Antibody Isotype
IgG2a, κ
Application
WB, E

Basic Information

Immunogen
BNIP2 (AAH02461, 1 a.a. ~ 314 a.a) full-length recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
BCL2/adenovirus E1B 19kDa interacting protein 2
Introduction
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. [provided by RefSeq]
Entrez Gene ID
663
UniProt ID
Q12982
Alternative Names
BNIP-2; NIP2
Function
Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.
Biological Process
Apoptotic process Source: MGI
Negative regulation of apoptotic process Source: UniProtKB
Polyphosphate catabolic process Source: GO_Central
Positive regulation of muscle cell differentiation Source: Reactome
Cellular Location
Cytoplasm; Perinuclear region. Localizes to the nuclear envelope region and to other cytoplasmic structures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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