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Mouse Anti-BOC Recombinant Antibody (CBYY-1729) (CBMAB-2078-YY)

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Datasheet
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Basic Information

Host Animal
Mouse
Clone
CBYY-1729
Application
WB
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BOC, Asp31-Asp852, Accession # Q9BWV1
Host Species
Mouse
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose
Preservative
None
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
BOC Cell Adhesion Associated, Oncogene Regulated
Introduction
The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforMouse. [provided by RefSeq, Sep 2014]
Entrez Gene ID
91653
UniProt ID
Q9BWV1
Alternative Names
BOC Cell Adhesion Associated, Oncogene Regulated; Cell Adhesion Associated, Oncogene Regulated 2; Brother Of CDON; Brother Of CDO; Boc Homolog (Mouse); Boc Homolog; Protein BOC; CDON2;
Function
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
Biological Process
Axon guidance Source: InterPro
Cell adhesion Source: UniProtKB-KW
Positive regulation of muscle cell differentiation Source: Reactome
Positive regulation of myoblast differentiation Source: HGNC
Smoothened signaling pathway Source: InterPro
Cellular Location
Cell membrane. Enriched at sites of cell-cell contact.
Topology
Extracellular: 31-855 aa
Helical: 856-876 aa
Cytoplasmic: 877-1114 aa
PTM
N-glycosylated.

Pedrosa, R. M., Wismans, L. V., Sinke, R., van der Weiden, M., van Eijck, C. H., Kros, J. M., & Mustafa, D. A. (2021). Differential Expression of BOC, SPOCK2, and GJD3 Is Associated with Brain Metastasis of ER-Negative Breast Cancers. Cancers, 13(12), 2982.

Nitta, Y., Miyachi, M., Tomida, A., Sugimoto, Y., Nakagawa, N., Yoshida, H., ... & Hosoi, H. (2019). Identification of a novel BOC-PLAG1 fusion gene in a case of lipoblastoma. Biochemical and biophysical research communications, 512(1), 49-52.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-BOC Recombinant Antibody (CBYY-1730) (CAT#: CBMAB-2079-YY)

Isotype control

For research use only. Not intended for any clinical use.

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