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Mouse Anti-BORCS5 Recombinant Antibody (1E1) (CBMAB-L0276-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to BLOC-1 Related Complex Subunit 5 (BORCS5). The antibody can be used for immunoassay techniques, such as IF, WB.
See all BORCS5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E1
Antibody Isotype
IgG2a
Application
IF, WB

Basic Information

Immunogen
Full length human recombinant protein of human LOH12CR1 produced in HEK293T cell.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
IF(ICC)1:4,000
WB1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
BLOC-1 Related Complex Subunit 5
Introduction
As part of the BORC complex, BORCS5 may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, BORCS5 may indirectly function in cell spreading and motility.
Entrez Gene ID
118426
UniProt ID
Q969J3
Alternative Names
BLOC-1 Related Complex Subunit 5; Myrlysin; Loss Of Heterozygosity; 12; Chromosomal Region 1; Myristoylated Lysosomal Protein; LOH12CR1; Loss Of Heterozygosity 12 Chromosomal Region 1 Protein; Loss Of Heterozygosity 12 Chromosomal Region 1; BLOC-1-Related Complex Subunit 5; LOH1CR12
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility.
Biological Process
Lysosome localization Source: UniProtKB
Organelle transport along microtubule Source: UniProtKB
Positive regulation of anterograde synaptic vesicle transport Source: GO_Central
Cellular Location
Lysosome membrane
PTM
Myristoylation at Gly-2 mediates attachment to lysosome membranes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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