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  • Rabbit Anti-BORCS6 Recombinant Antibody (CBLC008-LY)

Rabbit Anti-BORCS6 Recombinant Antibody (CBLC008-LY) (CBMAB-C9494-LY)

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Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
CBLC008-LY
Application
WB
Immunogen
Synthetic peptide corresponding to residues surrounding Glu270 of human C17orf59 protein.
Host Species
Rabbit
Specificity
Human, Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, pH 7.5, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
BLOC-1 Related Complex Subunit 6
Introduction
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
Entrez Gene ID
Human54785
Monkey716995
UniProt ID
HumanQ96GS4
MonkeyA0A2K5UNW9
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
Biological Process
Lysosome localization Source: UniProtKB
Cellular Location
Lysosome membrane

Araki, M., Ito, K., Takatori, S., Ito, G., & Tomita, T. (2021). BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice. Human Molecular Genetics, 30(17), 1618-1631.

Hartwig, C., Monis, W. J., Chen, X., Dickman, D. K., Pazour, G. J., & Faundez, V. (2018). Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC‐1 and BORC complexes. Developmental neurobiology, 78(3), 311-330.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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