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Mouse Anti-BTBD10 Recombinant Antibody (CBYY-0854) (CBMAB-0857-YY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-0854
Antibody Isotype
IgG3, κ
Application
WB, IP, IF, E, P

Basic Information

Immunogen
Amino acids 89-101 within an internal region of BTBD10 of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG3, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000
IHC-P1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
0.09% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
BTB Domain Containing 10
Introduction
Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells.
Entrez Gene ID
84280
UniProt ID
Q9BSF8
Alternative Names
BTB Domain Containing 10; Glucose Metabolism-Related Protein 1; BTB (POZ) Domain Containing 10; GMRP1; BTB (Broad-Complex Tramtrack And Bric-A-Brac/Pox Virus And Zinc Finger) Domain-Containing Protein 10; BTB/POZ Domain-Containing Protein 10; K+ Channel Tetramerization Protein; GMRP-1;
Function
Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells.
Biological Process
Negative regulation of neuron death Source: UniProtKB
Positive regulation of phosphorylation Source: UniProtKB
Type B pancreatic cell proliferation Source: UniProtKB
Cellular Location
Cytoplasm; Nucleus. Colocalizes with KCTD20 in filamentous structures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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