Mouse Anti-BTBD9 Recombinant Antibody (1G3) (CBMAB-A0895-LY)

Name: Mouse Anti-BTBD9 Recombinant Antibody (1G3)
SKU: CBMAB-A0895-LY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

1G3

Antibody Isotype

IgG2a, κ

Application

WB, E

Basic Information

Immunogen

BTBD9 (NP_689946, 2 a.a. ~ 70 a.a) partial recombinant protein with GST tag.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

BTB (POZ) domain containing 9

Entrez Gene ID

114781

UniProt ID

Q96Q07

Alternative Names

FLJ32945; KIAA1880; MGC120517; MGC120519; MGC120520; dJ322I12.1

Biological Process

Adult locomotory behavior Source: GO_Central
Circadian behavior Source: GO_Central
Circadian sleep/wake cycle, non-REM sleep Source: Ensembl
Long-term memory Source: Ensembl
Modulation of chemical synaptic transmission Source: GO_Central
Multicellular organismal iron ion homeostasis Source: Ensembl
Regulation of synaptic vesicle endocytosis Source: Ensembl
Sensory perception of temperature stimulus Source: Ensembl
Serotonin metabolic process Source: Ensembl

Involvement in disease

Restless legs syndrome 6 (RLS6): A neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, usually at night, inducing an irresistible desire to move the legs. The disorder results in nocturnal insomnia and chronic sleep deprivation. The majority of patients also have periodic limb movements in sleep, which are characterized by involuntary, highly stereotypical, regularly occurring limb movements that occur during sleep.

More Infomation

References

Fawzy, M. S., Fakhr-Eldeen, A., Abu AlSel, B. T., & Toraih, E. A. (2021). Molecular analysis of homeostatic iron regulator, transmembrane protease serine-6, and BTB domain-containing protein-9 variants and iron parameters in blood donors. Bioscience reports, 41(1), BSR20202584.

Chen, P., Zheng, F., Li, S., Cheng, H., Bornhorst, J., Li, Y., ... & Aschner, M. (2021). BTBD9 is a novel component of IGF signaling and regulates manganese-induced dopaminergic dysfunction. bioRxiv.

Li, L., Zhang, W., Liu, Y., Liu, X., Cai, L., Kang, J., ... & Jia, L. (2020). The CRL3 BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration. Signal transduction and targeted therapy, 5(1), 1-9.

Lyu, S., Doroodchi, A., Xing, H., Sheng, Y., DeAndrade, M. P., Yang, Y., ... & Li, Y. (2020). BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome. Brain Structure and Function, 225, 1743-1760.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-BTBD9 Recombinant Antibody (CBYY-0860)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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