Mouse Anti-C1QTNF1 Recombinant Antibody (4A10) (CBMAB-C6536-LY)

Name: Mouse Anti-C1QTNF1 Recombinant Antibody (4A10)
SKU: CBMAB-C6536-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

4A10

Application

E, WB

Immunogen

Recombinant protein corresponding to aa 26 - 281 of human CTRP1.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Preservative

None

Concentration

Batch dependent

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

C1q and tumor necrosis factor related protein 1

Introduction

C1QTNF1 (C1q And TNF Related 1) is a Protein Coding gene.

Gene Ontology (GO) annotations related to this gene include collagen binding.
An important paralog of this gene is C1QTNF6.

Entrez Gene ID

Human	114897
Mouse	56745
Rat	303701

UniProt ID

Human	Q9BXJ1
Mouse	Q9QXP7
Rat	Q5XIG2

Alternative Names

C1q And TNF Related 1; C1q And Tumor Necrosis Factor Related Protein 1; G Protein Coupled Receptor Interacting Protein; G Protein-Coupled Receptor-Interacting Protein; CTRP1; GIP; Complement C1q Tumor Necrosis Factor-Related Protein 1; ZSIG37;

Biological Process

Negative regulation of platelet activation Source: UniProtKB
Negative regulation of platelet aggregation Source: UniProtKB
Positive regulation of aldosterone secretion Source: UniProtKB
Positive regulation of cytosolic calcium ion concentration Source: UniProtKB
Positive regulation of gene expression Source: UniProtKB
Positive regulation of MAPK cascade Source: Ensembl
Positive regulation of protein kinase B signaling Source: Ensembl
Regulation of glucose metabolic process Source: Ensembl

Cellular Location

Secreted

Zarei, M., Khodakheyr, J. N., Rashidlamir, A., & Montazeri, A. (2021). The effect of combined resistance aerobic exercise training on concentrations of asprosin and complement C1q tumor necrosis factor-related protein-1 in men with type 2 diabetes. Sport Sciences for Health, 1-9.

Zhao, X., Li, Y., Yan, Y., Ma, X., & Guo, C. (2020). Methylation of CpG sites in C1QTNF1 (C1q and tumor necrosis factor related protein 1) differs by gender in acute coronary syndrome in Han population: a case–control study. Genes & genomics, 42(6), 681-689.

Kim, D., & Park, S. Y. (2019). C1q and TNF related protein 1 regulates expression of inflammatory genes in vascular smooth muscle cells. Genes & genomics, 41(4), 397-406.

Wu, L., Gao, L., Zhang, D., Yao, R., Huang, Z., Du, B., ... & Zhang, Y. (2018). C1QTNF1 attenuates angiotensin II-induced cardiac hypertrophy via activation of the AMPKa pathway. Free Radical Biology and Medicine, 121, 215-230.

Geiger, K., Muendlein, A., Leiherer, A., Saely, C. H., Brandtner, E. M., Larcher, B., ... & Drexel, H. (2018). The Association between the Adipokine C1QTNF1 and Type 2 Diabetes Is Significantly Modulated by Obesity. Circulation, 138(Suppl_1), A14846-A14846.

Muendlein, A., Leiherer, A., Saely, C. H., Geiger, K., Brandtner, E. M., Larcher, B., ... & Drexel, H. (2018). The novel adipokine C1QTNF1 significantly predicts the incidence of future major cardiovascular events in patients with type 2 diabetes. Circulation, 138(Suppl_1), A14687-A14687.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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