Mouse Anti-CA6 Recombinant Antibody (CBLC043-LY) (CBMAB-C9590-LY)

The product is antibody recognizes CA6 . The antibody CBLC043-LY immunoassay techniques such as: ELISA, IP, WB.
See all CA6 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBLC043-LY

Antibody Isotype

IgG2b

Application

ELISA, IP, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

5% trehalose

Concentration

0.5 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

carbonic anhydrase 6

Introduction

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.

Entrez Gene ID

765

UniProt ID

P23280

Alternative Names

CA-VI, GUSTIN

Function

Reversible hydration of carbon dioxide. Its role in saliva is unknown.

Biological Process

Bicarbonate transport Source: Reactome
Detection of chemical stimulus involved in sensory perception of bitter taste Source: UniProtKB
One-carbon metabolic process Source: GO_Central

Cellular Location

Secreted

References

Machlik, E., & Woll, E. E. (2021). The use of commercial ELISA kits in measuring CA6 concentration of saliva (Master's thesis, UiT Norges arktiske universitet).

Kormi, E. A., Pani, S. C., & AlNatsha, R. (2020). Association Between Salivary Carbonic Anhydrase 6 Levels and Early Childhood Caries in Children With Chronic Bronchial Asthma.

Mrag, M., Hamdouni, H., Gouiaa, A., Omezzine, A., Ben Amor, F., & Kassab, A. (2020). Investigation of carbonic anhydrase 6 gene polymorphism rs2274327 in relation to the oral health status and salivary composition in type 2 diabetic patients. Acta Odontologica Scandinavica, 78(8), 560-564.

Esberg, A., Haworth, S., Brunius, C., Holgerson, P. L., & Johansson, I. (2019). Carbonic anhydrase 6 gene variation influences oral microbiota composition and caries risk in Swedish adolescents. Scientific reports, 9(1), 1-12.

Patrikainen, M. (2019). Carbonic Anhydrase VI: Functional characterization in mouse and zebrafish model organisms.

Yrjänäinen, A. (2019). Biochemical and biophysical characterization of saliva-and milk human carbonic anhydrase VI: maidon ja syljen hiilihappoanhydraasi VI: n biokemiallinen ja biofysikaalinen karakterisointi (Master's thesis).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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